![]() Standard safety precautions must be followed, but as new research and clinical experience broaden our knowledge, changes in treatment and drug therapy may become necessary or appropriate. First published 1979 Second edition 1985 Third edition 1990 Fourth edition 1997 Fifth edition 2003 Sixth edition 2009 ISBN 978-0-7020-3096-3 British Library Cataloguing in Publication Data A catalogue record for this book is available from the British Library Library of Congress Cataloging in Publication Data A catalog record for this book is available from the Library of Congress Notice Medical knowledge is constantly changing. You may also complete your request on-line via the Elsevier homepage (), by selecting ‘Support and contact’ and then ‘Copyright and Permission’. ![]() Permissions may be sought directly from Elsevier’s Health Sciences Rights Department in Philadelphia, USA: telephone: (þ1) 2 fax: (þ1) 2 or, e-mail. No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of the Publishers. ![]() The right of Andrew D Bersten and Neil Soni to be identified as editors of this work has been asserted by them in accordance with the Copyright, Designs and Patents Act 1988. ![]() Neil Soni MB Chb MD FANZCA FRCA FJFICM CONSULTANT IN INTENSIVE CARE AND ANAESTHESIA, DIRECTOR AND LEAD CLINICIAN, INTENSIVE CARE UNIT, MAGILL DEPARTMENT OF ANAESTHESIA, INTENSIVE CARE AND PAIN MANAGEMENT HONORARY SENIOR LECTURER, IMPERIAL COLLEGE MEDICAL SCHOOL, CHELSEA AND WESTMINSTER HOSPITAL, LONDON, UKĪn imprint of Elsevier Limited # 2009, Elsevier Limited. Commissioning Editor: Michael Houston Development Editor: Helen Sofio (HS Publishing Services) Editorial Assistant: Susan Jansons Project Managers: Hemamalini Rajendrababu/Susan Stuart Design Manager: George Ayaji Illustration Manager: Kirsteen Wright Illustrator: Marion Tasker Marketing Manager (UK): Richard JonesĪndrew D Bersten MB BS MD FANZCA FJFICM PROFESSOR, DEPARTMENT OF CRITICAL CARE MEDICINE, FLINDERS MEDICAL CENTRE FLINDERS UNIVERSITY, ADELAIDE, AUSTRALIA ![]()
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